What kind of instrumental music? Have you experimented with different types? Maybe something more classical / less noticeable beats? What about just good headphones to block noise?
Good idea to check with doctor about how long your meds are lasting. Or – can you study at a different time of day and do less cognitive stuff in the evening once your meds have worn off?
I am finding lately that I have days that I am more sensitive to noise than others – and there doesn’t seem to be rhyme or reason to it. That’s the fun part of this whole experience – some days you know why you have “off days”, some days are just because.